Endocrine Abstracts

Background: There is concern that adolescents with childhood-onset GHD (COGHD) and persistent GH deficiency may be exposed to multiple metabolic risks after GH treatment withdrawal at the attainment of final height (FH).Aim: Aim of our study is to retrospectively compare growth response and metabolic profile in isolated idiopathic COGHD adolescents with permanent GH deficiency in comparison to GHD subjects who normalized their GH response at transition p...

Background: Thyroid hormone plays a key role in bone mineral homeostasis and significant alterations in its circulating levels has been associated with impairment in skeletal growth during childhood. To date, bone effects of subclinical hypothyroidism (SH) has not been demonstrated yet, therefore the management of this condition is still debated.Aim: To evaluate bone mineral density (BMD) in children with mild, persistent SH and the effects of two-years ...